IOC or IoC may refer to:
Computing
- IBM Open Class
- Input/Output Controller
- Inversion of Control, a software design pattern
Telecom
- Independent Operating Company, usually a synonym to CLEC
Game
- Invasion of Chaos, a booster pack in the Trading Card Game Yu-Gi-Oh! which shaped an entire metagame
Other
- Indian Ocean Commission, generally COI, but according to World Bank as well IOC
- Icon of Coil
- Indian Oil Corporation
- Initiatives of Change
- Intergovernmental Oceanographic Commission
- International Olympic Committee
- International Organized Crime
- Initial Operating Capability
- International Oil Company, as opposed to NOC, which stands for National Oil Company
- International Ornithological Congress
- Iron Ore Company of Canada
- Italian Organized Crime
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